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Men with high cholesterol are more exposed to heart attacks

Men with high cholesterol levels are more likely to have heart problems. They have a risk of heart attacks three times higher than women with the same level of cholesterol. This fact is confirmed by the study of Norwegian scientists. Surveys were analyzed 45,000 patients

Cephalexin. Indications and benefits

What is cephalexin Cephalexin belongs to a class of antibiotics called cephalosporins. Its action prevents bacteria cell wall synthesis whereby the bacteria are killed. The antibiotic is active against wide range of bacterial strains. Indications Cephalexin used for combating infections caused by bacteria sensitive to

Eliminating lymphatic filariasis in Port-au-Prince

A mass albendazole administration was successful in eliminating lymphatic filariasis in Port-au-Prince, Haiti, in 71% cases. Lymphatic filariasisis is an infection caused by worm Wuchereria bancrofti associated with lymphedema and hydrocele. It has been a large scale global problem for a long time. The drug

Coffee prevents hepatocellular carcinoma

New research made by staff of the Institute of Pharmacological Research in Milan found that coffee reduces the risk of developing hepatocellular carcinoma (the most common type of liver cancer) by 40%. According to the author of the research, Carlo La Vecchia, drinking three cups

Proteins to fight viruses

Israeli scientists have identified a necessary protein that destroys viruses. This is the first step to create an alternative for medications. The protein stops virus from splitting, ruining and fighting attacks. In the long run, a new “antibiotic” can be created from this necessary protein.

Men with high cholesterol are more exposed to heart attacks

heart problemsMen with high cholesterol levels are more likely to have heart problems. They have a risk of heart attacks three times higher than women with the same level of cholesterol. This fact is confirmed by the study of Norwegian scientists.

Surveys were analyzed 45,000 patients who had blood tests. During the study 500 men and 157 women at least once experienced a heart attack. Special risk group included men of middle and old age: the risk of developing heart disease in combination with high cholesterol levels was three times higher.

Smoking and genetic predisposition to diseases of the cardiovascular system aggravate the situation. So people need constant prevention, timely diagnosis of the disease and early qualified medical aid to combat cholesterol. The most affordable way to fight – balanced diet and exercises. When results are static it is necessary to switch on medications.

Scientists can not accurately determine the cause of such a large difference in the risk of heart attack in men and women for a while. Perhaps this occurs due to protective properties of female hormones -estrogens.

Cephalexin. Indications and benefits

What is cephalexin

cephalexin tabletsCephalexin belongs to a class of antibiotics called cephalosporins. Its action prevents bacteria cell wall synthesis whereby the bacteria are killed. The antibiotic is active against wide range of bacterial strains.

Indications

Cephalexin used for combating infections caused by bacteria sensitive to the drug. The drug is used most often to fight infection of the urinary tract and respiratory tract. It is a semi-synthetic cephalosporin antibiotic, belongs to the first generation of these antibiotics. Cephalexin is intended for oral use. It works by inhibiting bacterial cell wall synthesis, which prevents the multiplication of bacterial cells. Due to the chemical structure is considered to be cephalexin is beta-lactam antibiotics, whose common feature is the presence in the molecule of the beta-lactam ring. This structure is sensitive to the action of enzymes, so-called. beta-lactamases produced by some bacteria. Beta-lactamase present in bacterial cells, and may cause degradation and inactivation of the antibiotic particles are one of the causes of bacterial resistance to antibiotics. Cephalexin, like other first generation cephalosporins has a relatively low resistance to beta-lactamases. Used to treat infections of the respiratory tract, urinary and soft tissue.

The advantages of this drug is a broad spectrum of antimicrobial activity, including aerobic and anaerobic pathogens, stability to the action of β- lactamases of staphylococci, enterobacteria and some anaerobes (fuzobakterii, Bacteroides, prevotell) . However, amoxicillin/clavulanate inactive against P.aeruginosa. In the case of microbiologically confirmed Pseudomonas etiology is necessary to use local (3 % acetic acid, ciprofloxacin) and systemic medications (azlocillin, piperacillin, ticarcillin, ceftazidime, ceftazidime, cefepime, aztreonam, ciprofloxacin). All of these AMPs is desirable to use in combination with aminoglycosides (netilmicin, amikacin). Drugs used in large doses, duration of therapy should be 2 weeks (minimum) to 6 weeks (except aminoglycosides, which impose no more than 7-14 days).

Benefits of cephalexin

Cephalexin advantage is that it has not resistant those microorganisms that have developed immunity to the antimicrobial penicillin. Due to this, cephalexin used successfully in the case of protracted tracheitis, bronchitis, sore throats and tonsillitis. A significant drawback of cephalexin – its inability to overcome brain barrier and penetrate the lining of the brain. This eliminates the possibility of its use in the treatment of generalized sepsis, encephalitis and meningitis of any etiology.

Eliminating lymphatic filariasis in Port-au-Prince

A mass albendazole administration was successful in eliminating lymphatic filariasis in Port-au-Prince, Haiti, in 71% cases.

Lymphatic filariasisis is an infection caused by worm Wuchereria bancrofti associated with lymphedema and hydrocele. It has been a large scale global problem for a long time.

The drug administration covered more than 65% of citizens, according to the report. The first mass drug administration in Port-au-Prince took place from November 2011 through 2012. 71% of persons were taking albendazole.

It’s estimated that about 120 million people all over the world are suffering from lymphatic filariasis, and Haiti was among those 4 the most endemic. WHO estimates the elimination of the disease by 2020, due to mass administration of anthelmintic drugs. By 2011, at least one round of mass drug administration of albendazole and diethylcarbamazine (Hetrazan, Lederle) had been issued to all endemic areas in Haiti except for Port-au-Prince.

The researchers evaluated coverage in Port-au-Prince by conducting a stratified, three-stage cluster-sample survey in seven strata: internally displaced person (IDP) camps in six communes comprised one stratum, and non-IDP camp households in each of the six communes comprised six strata. A total of 6,345 adults answered for themselves and/or others in the household about taking the tablets, and 71% had taken the drugs.

The researchers found that 88% of the respondents knew about the mass drug administration before it began. Only half of the people who did not hear about it in advance took the tablets, compared with 74% of people who did hear about it in advance.

The coverage demonstrates that despite substantial obstacles posed by recent natural disasters and public health emergencies, Haiti has taken an important step toward meeting the challenge of lymphatic filariasis.

The source:Mass eliminating lymphatic filariasis in Port-au-Prince, Haiti

Coffee prevents hepatocellular carcinoma

New research made by staff of the Institute of Pharmacological Research in Milan found that coffee reduces the risk of developing hepatocellular carcinoma (the most common type of liver cancer) by 40%.

According to the author of the research, Carlo La Vecchia, drinking three cups a day reduce this probability by more than 50%. He believes that such a favorable effect of coffee for the health of the liver may be achieved due to the fact that it helps to prevent diabetes – a risk factor for liver disease.

The researchers conducted a meta-analysis of 16 major studies published in 1996 and 2012. In total, they studied more than 3000 cases of liver cancer. Experts still do not know whether coffee played an important role in the prevention of liver cancer. So they plan to continue their studies, and at the moment is better to address to proven prevention methods.

Previously, scientists from the American Cancer Society in Atlanta found that four cups of coffee reduces the risk of developing oral cancer. Scientists from the Graduate School of Medicine of the National University of Singapore found that the drink reduces the risk of fatty liver disease – a disease of the accumulation of fat in the liver, which occurs in non-drinking people, and their colleagues from the University of Queensland believe that coffee helps to lose weight as appetite suppressant. Japanese experts have concluded that the daily consumption of coffee can reduce the risk of stroke by 20%.

Proteins to fight viruses

Israeli scientists have identified a necessary protein that destroys viruses. This is the first step to create an alternative for medications. The protein stops virus from splitting, ruining and fighting attacks. In the long run, a new “antibiotic” can be created from this necessary protein.

This is the first major breakthrough in the war between bacteriophages and virus. “Although there is still a lengthy way to go before the execution level, this research can provide as a foundation for anti-biotic treatment later.

In latest years, the level of resistance of virus to medications has considerably improved, making present day medicine sometimes incapable to battle attacks and microbial illnesses. This problem was as one of the three biggest risks to public health.

Soon after the use of medications started to become extensive, the level of resistance of virus to medications was rising. Since then, the trend has complicated mostly because of the expansion of the common life expectancy and the breakdown of our immunity processes. Bacteriophages, found in the beginning aspect of the past millennium, were for a lengthy period regarded a potential buddy in the war on disease within your body and have been substantially used in Southern European nations. However, they were mostly discontinued by European medicine, aspect because their action is very nearby in comparison to medications.

In comparison with virus, bacteriophages (also known as simply as phages) do not damage humans. They connect themselves to bacteria, treating it with DNA and quickly recreate within it. The microbial cell keeps on elongating until it is gradually damaged. Bacteriophages are the most common life form on this planet.

Viruses are swarmed with bacteriophages, which are their natural opponents and which in most cases eliminate them. Ever since the finding of bacteriophages in the beginning of last millennium, scientists have recognized that, on the most crucial of the enemy of your attacker is your buddy, medical use could be created of phages to battle virus.

Bacteria know how to create a certain level of potential to deal with phages – they have protection system that they use against them. Nevertheless, more use will be created of phages because of the recession in the finding of new medications.